The following conditions increase the need for vitamin C:
(1) Patients undergoing chronic hemodialysis, gastrointestinal diseases (long-term diarrhea, gastric or ileal resection), tuberculosis, cancer, ulcer disease, hyperthyroidism, fever, infection, Trauma, burns, surgery, etc.;
(2) patients receiving parenteral nutrition due to strict control or choice of diet, due to malnutrition, sudden weight loss, and during pregnancy and lactation;
(3) application of barbiturates and tetracyclines Class, salicylic acid, or vitamin C as a urinary system acidifier.